Diabetes or Diabetes Mellitus (DM), in Greek means translucent or shower water, and from the Latin meaning sweet taste, while in Indonesia DM is better known as diabetes, in which glucose (simple sugar) in the blood become high because the body can not produce or secrete enough insulin. And from some tests directly, generally the urine of diabetics was sweet because it contains a lot of sugar.
Every food we eat is converted into energy by the body. In the stomach and intestine, food is broken down into a number of basic elements, including one type of sugar, called glucose. If there is sugar, the pancreas produces insulin, which helps the flow of sugar into the body's cells. Then, the sugar can be absorbed well in the body and burned to produce energy.
When people suffer from diabetes, the pancreas that person can not produce enough insulinuntuk absorb sugar from food. That which causes blood sugar levels to be high due to the pile of sugar from food that can not be absorbed properly and burned into energy. Another cause is a defective insulin or the body can not use insulin baik.1-6
The composition of the recipe as berikut1:Simlisia
Potion
Partin use
Total processed
How though
DoseAdditional
sambiloto
Leaf
1 / 8ggm
Boiled in 3 cups of water, up to ¾ cup water
3x a dayMain
Cat whiskers
Leaf
1 / 8ggmMain
brotowali
Batabg
3 / 4gr
Crude drug name, Writing nomenclature, respectively efficacy
I. Additional Simplisasambiloto
Bitter plant has the latin name Andrographis paniculata Ness has Justicia synonym paniclata Burn; Justicia latebrosa Russ. With the name of the area: Papaitan, Ki peurat or bidara.Efficacy and BenefitsInvitro bitter plant have antidiabetic properties by influencing the secretion of insulin from the islets of Langerhans. Leaves or bitter herbs used in traditional medicine among others, for dysentery, diabetes, fever, headache, snake venom antidote, tonic, skin diseases and tifus.1-5preclinical dataData percent rise in blood glucose concentrations are presented in Figures 1 and 2, obtained from the difference in blood glucose concentration at a particular time (Ct) with initial blood glucose concentration, ie before the induction of diabetes with glucose (Co) divided by Co, multiplied by 100%. Presentation of data in the form of curves to easily compare the effect given by the materials testing and comparison. The test is performed on galus Wistar rats. Judging by using a variable time. Hypoglycemic effect given by the ethanol extract can be seen in the pace of decline in blood glucose concentrations at minute 60 and 90, although the concentration of glucose in the 30th minute and 60 is greater than the control. This data is amplified by the fact that tolbutamide which is an antidiabetic drug also provides blood glucose concentrations were higher than the control in the 30th minute. Active ethanol extract showed that hypoglycemic activity is given by the polar components of bitter herbs. This suggests that the traditional way of usage is done by boiling the bitter herbs and drink boiled water is the method tepat.6
CAT WHISKERS
name SimplisiaCats whiskers which has the Latin name Orthosiphon aristatus B1. Plant cat's whiskers (Orthosiphon aristatus B1) are perennials that included in the family Laminaceae (PACI-pacian). These plants come from India, then spread to several countries such as the USA, the Philippines, Papua New Guinea, Africa, Central Asia, the Pacific Islands, Australia and Indonesia. Cat's whiskers (Orthosiphon aristatus B1) synonymous with O. grandiflorus Bold and O. Stamineus Bent. The local name for this plant is remujung (Java), sesalaseyan and songkot koceng (Madura) and whiskers (Sunda) .5
Reason
In Indonesia, cat whiskers as traditional medicine, has long been recognized by the public, especially in rural areas. In the world of modern medicine, botanicals leaves cat whiskers have got the position / main attention for use as a drug that is classified fitoterapi.5
Pre Clinical TestDiabetes mellitus is a common disease in Malaysia and is expected to increase to 2.48 million people with diabetes during 2030. Orthosiphon Stamineus, Benth (O. Stamineus) is an herb that is traditionally used in Malaysia to treat kidney problems, gout, and diabetes mellitus. Interaction between modern medicine and Stamineus O. still unknown. This study was conducted to examine the effect of oral administration of 14 days of the methanol extract of leaves of O. Stamineus in phase I and phase II liver enzymes in drug metabolism in STZ-induced in Sprague-Dawley (SD) rats exposed to diabetes. Aminopyrine, p-
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